Title :
Photon Density Measured Over a Cut Surface: Implications for Optical Mapping of the Heart
Author_Institution :
Dept. of Phys., Oakland Univ., Rochester, MI
Abstract :
During optical mapping of the heart, the signal represents a weighted average of the transmembrane potential. Researchers sometimes illuminate the epicardium and record over a cut surface. My goal is to compare their signal to the photon density within an intact tissue. Does cutting the tissue affect the signal?
Keywords :
bio-optics; bioelectric phenomena; biological tissues; biomedical measurement; biomembranes; cardiology; diffusion; epicardium; heart; intact tissue; optical mapping; photon density; photon diffusion equation; transmembrane potential; Density measurement; Equations; Heart; Light scattering; Lighting; Optical recording; Optical scattering; Optical surface waves; Particle scattering; Signal mapping; Optical mapping; optical mapping; photon diffusion equation; transmembrane potential; Algorithms; Body Surface Potential Mapping; Computer Simulation; Heart; Humans; Light; Models, Biological; Photometry; Radiation Dosage; Radiometry;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2008.925293
