Title :
Closed-Loop Regulation of a Physiological Parmeter by an IPFM/SDC (Integral Pulse Frequency Modulated/Smith Delay Compensator) Controller
Author :
Woodruff, Eileen A. ; Northrop, Robert B.
Author_Institution :
Biomedical Engineering Laboratories, Department of Electrical and Systems Engineering, University of Connecticut
Abstract :
This theoretical paper discusses the realization of a discrete, closed-loop control system which uses an integral pulse frequency modulated/Smith delay compensator (IPFM/SDC) controller to regulate an in vivo physiological parameter to the prescribed quantity in real time. The pharmacokinetic (PK) plant considered is the sodium nitroprusside (SNP) blood-pressure plant. The simulated plant is appropriately time-and amplitude-scaled using op-amps and RC active filter elements.
Keywords :
Biomedical engineering; Blood pressure; Control systems; Delay effects; Drug delivery; Frequency modulation; Microcomputers; Open loop systems; Pulse modulation; Sensor systems; Biomedical Engineering; Blood Pressure; Feedback; Humans; Infusion Pumps; Models, Biological; Nitroprusside;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1987.326070
