DocumentCode
1221566
Title
Recent progress in microfluidic devices for nucleic acid and antibody assays
Author
Selvaganapathy, Ponnambalam Ravi ; Carlen, Edwin T. ; Mastrangelo, Carlos H.
Author_Institution
Dept. of Electr. Eng. & Comput. Sci., Michigan Univ., Ann Arbor, MI, USA
Volume
91
Issue
6
fYear
2003
fDate
6/1/2003 12:00:00 AM
Firstpage
954
Lastpage
975
Abstract
Microfluidic devices are increasingly important in biomedical assays. In this paper, we review recent progress on these devices for chemical amplification, hybridization, separation, and detection of nucleic acids. Recent developments in microfluidic technologies for detection of protein binding events in immunoassay applications are also reviewed.
Keywords
biological techniques; macromolecules; microfluidics; molecular biophysics; antibody assay; biomedical assay; chemical amplification; hybridization chip; microfluidic device; nucleic acid assay; protein binding immunoassay; separation microdevice; Biochemistry; Chemicals; DNA; Genetics; Immune system; Laboratories; Microfluidics; Micromechanical devices; Performance analysis; Proteins;
fLanguage
English
Journal_Title
Proceedings of the IEEE
Publisher
ieee
ISSN
0018-9219
Type
jour
DOI
10.1109/JPROC.2003.813569
Filename
1206673
Link To Document