DocumentCode
1222283
Title
Computer Aided Analysis of Cell-Cycle Phase from Cytophotometric Histogram
Author
Kosugi, Yukio ; Ikebe, Jun ; Sekine, Matsuo ; Musha, Toshimitsu ; Shitara, Nobuyuki ; Kohno, Takeshi ; Takakura, Kintomo
Author_Institution
Research Laboratory of Precision Machinery and Electronics, Tokyo Institute of Technology
Issue
5
fYear
1978
Firstpage
429
Lastpage
434
Abstract
A method for estimating, from cytophotometric data, the proportion of cells in three different phases of the cell cycle is proposed. Computation is done by means of determining seven parameters in the approximate function for the fluorescence intensity histogram. The proportion of cells in the GI, S, and G2-M phases, obtained by this method, was found to be reliable.
Keywords
Cells (biology); Computer aided analysis; DNA; Fluorescence; Histograms; Laboratories; Machinery; Neurosurgery; Phase estimation; Tumors; Cell Cycle; Computers; Fluorescence; Lymphocytes; Photometry;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.1978.326340
Filename
4122873
Link To Document