Title :
Comments on "Some Observations on the Physical Realizability of Compartmental Models with Delays
Author :
Brown, R.F. ; Godfrey, K.R.
Author_Institution :
School of Electrical Engineering, University of New South Wales
Abstract :
A recent communication concluded that a linear differential-difference model presented by Bellman is structurally unrealizable. It is shown here that while the model is indeed unrealizable by a linear compartmental model, it is, in fact, structurally realizable by a linearized nonlinear compartmental model. The potential biological meaningfulness of this result is demonstrated for a simple model of a batch purifier process.
Keywords :
Art; Biological system modeling; Biomedical computing; Biomedical measurements; Blood flow; Communication system control; Delay effects; Fluid flow measurement; Steel; Temperature measurement; Mathematics; Models, Biological; Time Factors;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1979.326549
