Title :
Automatic Continuous-Time Blood Pressure Control in Dogs by Means of Hypotensive Drug Injection
Author_Institution :
School of Electrical Engineering, Purdue University
Abstract :
An automated drug administration system is proposed to control the decrease in the mean arterial blood pressure of dogs. It is accomplished by identifying a model for the open loop system consisting of a syringe pump and a dog. A linear feedback controller is then determined by solving an inverse optimum control problem. The chosen controller is optimal relative to a quadratic critexion. The controller is designed so that the mean arterial blood pressure is maintained at a desired level.
Keywords :
Adaptive control; Arterial blood pressure; Automatic control; Blood pressure; Control systems; Dogs; Drugs; Linear feedback control systems; Open loop systems; Pressure control; Animals; Dogs; Ferricyanides; Hypotension, Controlled; Models, Biological; Nitroprusside;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1980.326579