Title :
Theoretical Validation of the Thermal Dilution Method for Cardiac Output Determination
Author :
Nitzan, M. ; Weinreb, A. ; Appelbaum, A.
Author_Institution :
Division of Medical Physics, Racah Institute of Physics, The Hebrew University of Jerusalem
Abstract :
The basic formula of the thermal dilution method for the measurement of cardiac output is proven for pulsatile flow, assuming constant stroke rate, equal stroke volumes, and ideal ventricular mixing. Firstly, for an ideal thermistor of negligible response time which presents the temperature of the blood in the pulmonary artery as a step function; then it is shown that the area under the curve of temperature versus time is independent of the response time of the thermistor; hence, the formula holds for all thermistors.
Keywords :
Animals; Biomedical measurements; Delay; Humans; Measurement errors; Statistical analysis; Statistical distributions; Stochastic processes; Temperature; Thermistors; Cardiac Output; Humans; Stroke Volume; Temperature; Thermodilution;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.1980.326585
