Cortical activation by fNIRS and fMRI during grasping in patient with traumatic brain injury: A case study

This study is to observe the cortical activation pattern by fNIRS and fMRI during grasping in patient with TBI. PMA, SMA, M1, and S1 were focused on the analysis of cortical activations. The measured BOLD and HbR signals were t-statistically analyzed using SPM and NIRS-SPM, respectively. The results showed that contralateral M1 and SM1 were mainly activated during non-affected hand(left) grasping in both fNIRS and fMRI (fNIRS: p<;0.05, fMRI: p<;0.001). The SMA was activated with non-affected hand(left) movements after fMRI analysis. On the other hand, the ipsilateral M1 and SM1 was activated with the affected hand(right) movements(fNIRS: p<;0.05, fMRI: p<;0.001). fNIRS revealed similar cerebral cortical activation to fMRI. As expected, fNIRS could be a powerful candidate of brain mapping of TBI patients.