DocumentCode :
1225588
Title :
Modelling current transport through DNA (deoxyribonucleic acid) molecules using equivalent circuits
Author :
Kwok, H.L.
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Victoria, BC, Canada
Volume :
151
Issue :
6
fYear :
2004
Firstpage :
193
Lastpage :
196
Abstract :
The current transport properties of DNA molecules are of considerable interest. The key reason for this appears to be linked to the universality of DNA molecules in living organisms, their self-assembly properties, and potential applications as nanoscale devices. The modelling of the I-V characteristics of a DNA molecule using equivalent circuits is reported. The advantages of the proposed model are that non-linear current behaviour can be included together with potential piece-wise solutions. The model includes the use of transistors to mimic current discontinuities at transition points. The simulated results closely resemble measured I-V curves and do not invoke resonant tunneling which contradicts observed temperature dependences. An equivalent-circuit model which includes the use of active devices is shown to be effective way to mimic non-linear current transport in biological molecules.
Keywords :
DNA; bioelectric phenomena; electric current; equivalent circuits; molecular biophysics; physiological models; DNA molecules; current transport; deoxyribonucleic acid; equivalent circuits; nanoscale devices; nonlinear current behaviour; piecewise solutions; self-assembly;
fLanguage :
English
Journal_Title :
Nanobiotechnology, IEE Proceedings -
Publisher :
iet
ISSN :
1478-1581
Type :
jour
DOI :
10.1049/ip-nbt:20045007
Filename :
1389210
Link To Document :
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