DocumentCode :
1225918
Title :
Numerical investigation of the electric field distribution induced in the brain by transcranial magnetic stimulation
Author :
Kim, D.-H. ; Sykulski, J.K. ; Loukaides, N. ; Georghiou, G.E.
Author_Institution :
Sch. of Electr. Eng. & Comput. Sci., Kyungpook Nat. Univ., Daegu, South Korea
Volume :
151
Issue :
6
fYear :
2004
Firstpage :
479
Lastpage :
483
Abstract :
Results are presented on the prediction and optimisation of the electric field distribution obtained during transcranial magnetic stimulation (TMS) for deep neuron stimulation by using the finite-element method (FEM) in three dimensions. The effects of the geometrical models of the head on the distribution and penetration of the electric field induced in the brain during TMS are examined. For a magnetic field that can penetrate deeply and safely to activate the brain´s central structures, an iron core is introduced and its core shape is optimised using continuum design sensitivity analysis (CDSA) combined with the FEM. It is revealed that the incorporation of an accurate brain model in terms of shape as well as conductivity values is crucial for improved estimation of the field distribution. The introduction of an optimised iron core is shown to enhance the magnitude and localisation of the electric field induced inside the brain.
Keywords :
bioelectric phenomena; biological effects of fields; biomagnetism; brain models; finite element analysis; patient treatment; FEM; brain central structure; brain model; conductivity; continuum design sensitivity analysis; deep neuron stimulation; electric field distribution; electric field localisation; electric field penetration; finite element method; head geometrical models; iron core shape optimization; optimisation; transcranial magnetic stimulation;
fLanguage :
English
Journal_Title :
Science, Measurement and Technology, IEE Proceedings -
Publisher :
iet
ISSN :
1350-2344
Type :
jour
DOI :
10.1049/ip-smt:20040861
Filename :
1389247
Link To Document :
بازگشت