• DocumentCode
    1228307
  • Title

    Simulation of action potentials in a one-dimensional bidomain

  • Author

    Barach, John Paul

  • Author_Institution
    Dept. of Phys. & Astron., Vanderbilt Univ., Nashville, TN, USA
  • Volume
    35
  • Issue
    5
  • fYear
    1988
  • fDate
    5/1/1988 12:00:00 AM
  • Firstpage
    340
  • Lastpage
    345
  • Abstract
    An approximate method of calculating action potentials in a nerve fiber within a coaxial sheath is presented. The method is of the implicit type, but it avoids any large matrix inversion and is adapted to run conveniently on a small PC/AT. It produces traces of the extracellular voltage V out, which is not calculated by other methods, as well as the intracellular potentials V in. For homogeneous fibers with small sheath resistance, V out is proportional to d 2V in/dz 2, as expected. In more complex cases, V out remains small, but its shape is hard to predict. One such example is presented in which an extracellular voltage trace of novel shape is calculated.
  • Keywords
    bioelectric potentials; neurophysiology; physiological models; 1D domain; action potentials calculation method; coaxial sheath; extracellular voltage trace; nerve fiber; sheath resistance; Biomembranes; Coaxial components; Extracellular; Nerve fibers; Nonlinear equations; Optical fiber cables; Physics; Shape; Transmission line matrix methods; Voltage; Action Potentials; Computer Simulation; Extracellular Space; Models, Neurological; Nerve Fibers; Neural Conduction;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/10.1391
  • Filename
    1391