Title :
Simulation of action potentials in a one-dimensional bidomain
Author :
Barach, John Paul
Author_Institution :
Dept. of Phys. & Astron., Vanderbilt Univ., Nashville, TN, USA
fDate :
5/1/1988 12:00:00 AM
Abstract :
An approximate method of calculating action potentials in a nerve fiber within a coaxial sheath is presented. The method is of the implicit type, but it avoids any large matrix inversion and is adapted to run conveniently on a small PC/AT. It produces traces of the extracellular voltage V out, which is not calculated by other methods, as well as the intracellular potentials V in. For homogeneous fibers with small sheath resistance, V out is proportional to d 2V in/dz 2, as expected. In more complex cases, V out remains small, but its shape is hard to predict. One such example is presented in which an extracellular voltage trace of novel shape is calculated.
Keywords :
bioelectric potentials; neurophysiology; physiological models; 1D domain; action potentials calculation method; coaxial sheath; extracellular voltage trace; nerve fiber; sheath resistance; Biomembranes; Coaxial components; Extracellular; Nerve fibers; Nonlinear equations; Optical fiber cables; Physics; Shape; Transmission line matrix methods; Voltage; Action Potentials; Computer Simulation; Extracellular Space; Models, Neurological; Nerve Fibers; Neural Conduction;
Journal_Title :
Biomedical Engineering, IEEE Transactions on