Tissue spectroscopy with electrical impedance tomography: computer simulations

Author

Griffiths, H.

Author_Institution

Inst. Nat. de la Sante et de la Recherche Med., Lyon, France

Volume

42

Issue

9

fYear

1995

Firstpage

948

Lastpage

954

Abstract

A method is proposed by which bioelectrical spectroscopy could be combined with electrical impedance tomography (EIT) to provide noninvasive characterization of tissue. Multifrequency (2-200 kHz) EIT measurements were simulated with a numerical model for a volume of porcine liver immersed in an electrolytic tank. From the reconstructed EIT images the tissue characterization method was then applied enabling a plot of complex resistivity to be drawn for any selected pixel in the image. Simulations were performed for a small volume of degraded tissue embedded in the normal tissue to examine its effect on the derived spectroscopic parameters. The method could have an application in transplant surgery for screening organs for tissue degradation.

Keywords

digital simulation; electric impedance imaging; medical image processing; spectroscopy; 2 to 280 kHz; bioelectrical spectroscopy method; complex resistivity plot; degraded tissue; electrical impedance tomography; electrolytic tank immersion; medical imaging; noninvasive tissue characterization; normal tissue; organs screening; porcine liver; reconstructed images; tissue degradation; transplant surgery; Bioelectric phenomena; Computational modeling; Computer simulation; Degradation; Electrochemical impedance spectroscopy; Liver; Numerical models; Numerical simulation; Tomography; Volume measurement; Animals; Computer Simulation; Electric Impedance; Electrodes; Electrolysis; Electrophysiology; Liver; Models, Biological; Swine; Tomography;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.412664

Filename

412664