Impedance modeling of the intracortical microelectrode for a reliable design of a brain activity recording system

The possibility to use an electrical model empirically tuned with the probe impedance detected by in vivo measurements for intracortical signal monitoring is here described. The proposed model allows to make a reliable pre-amplification stage design that can follow the changes in the probe impedance after its implant for a long term recording. Here simulation results are compared with in vivo measurements and the possibility to adapt empirically the model looks promising and gives space for further investigations.