Title :
A Data-Mining Approach for Investigating Social and Economic Geographical Dynamics of
-Thalassemia's Spread
Author :
Akay, Altug ; Dragomir, Andrei ; Yardimci, Ahmet ; Canatan, Duran ; Yesilipek, Akif ; Pogue, Brian W.
Author_Institution :
Spaulding Rehabilitation Hosp., Boston, MA, USA
Abstract :
beta-Thalassemia is an anemic genetic disorder that remains a major global health issue, especially in the globalized era where public health, economics, and education are tightly interwoven. Previous studies have examined the disease´s rate and heredity. This study analyzed beta-thalassemia´s socioeconomic geography and how it affects the afflicted population. We processed survey data and performed data mining using self-organizing maps to identify underlying data structure. We hypothesized that certain variables mark subgroups within the affected population and we aimed at identifying these subgroups and used a correlation-based measure to assess the variable´s importance to the subgroup´s distinction. The population´s education level was one of the major factors that divided it into different subgroups. Our study showed that recurring patterns of specific variables separated the affected population into disparate subgroups based on their response to questionnaires. Future studies can use such tools to delve deeper into how other variables (e.g. socioeconomic and genomic) can identify subgroups within larger affected populations.
Keywords :
data mining; diseases; medical administrative data processing; self-organising feature maps; socio-economic effects; anemic genetic disorder; beta-thalassemia; correlation; data structure; data-mining; disease heredity; disease rate; education; population education level; public health; self-organizing map; socioeconomic geographical dynamics; $beta$ -thalassemia; Data mining; self-organizing map; Cluster Analysis; Data Mining; Geography; Humans; Reproducibility of Results; Socioeconomic Factors; Turkey; beta-Thalassemia;
Journal_Title :
Information Technology in Biomedicine, IEEE Transactions on
DOI :
10.1109/TITB.2009.2020062