Neuroblastoma Cells Displacement by Magnetic Carbon Nanotubes

Author

Pensabene, V. ; Vittorio, O. ; Raffa, V. ; Ziaei, A. ; Menciassi, A. ; Dario, P.

Author_Institution

Italian Inst. of Technol. (IIT), Univ. of Genova, Genova

Volume

7

Issue

2

fYear

2008

fDate

6/1/2008 12:00:00 AM

Firstpage

105

Lastpage

110

Abstract

In this paper, as-produced multiwall carbon nanotubes (MWNTs) have been analyzed by scanning electron microscopy and energy dispersive X-ray spectrometry, revealing the presence of Fe, Al, and Zn residuals and impurities. MWNTs have then been dispersed in Pluronic F127 aqueous solution and used to seed neuroblastoma cell lines (HN9.10e and SH-SY5Y) for three days. We found that MWNTs interact with cells and induce, under a permanent constant magnetic field, the cell displacement toward the magnetic source.

Keywords

X-ray spectroscopy; biological effects of fields; biomagnetism; carbon nanotubes; cellular biophysics; scanning electron microscopy; Al residuals; Fe residuals; Pluronic F127 aqueous solution; Zn residuals; energy dispersive X-ray spectrometry; impurities; magnetic carbon nanotube; multiwall carbon nanotubes; neuroblastoma cells displacement; permanent constant magnetic field; scanning electron microscopy; Cancer; Carbon nanotubes; Dispersion; Drugs; Impurities; Magnetic analysis; Magnetic fields; Medical treatment; Scanning electron microscopy; Spectroscopy; Carbon nanotubes (CNTs); magnetic materials; tumor cell displacement; Cell Line, Tumor; Cell Movement; Cell Separation; Humans; Magnetics; Micromanipulation; Nanotechnology; Nanotubes, Carbon; Neuroblastoma;

fLanguage

English

Journal_Title

NanoBioscience, IEEE Transactions on

Publisher

ieee

ISSN

1536-1241

Type

jour

DOI

10.1109/TNB.2008.2000749

Filename

4537998