DocumentCode :
1266907
Title :
A multiple circular path convolution neural network system for detection of mammographic masses
Author :
Lo, Shih-Chung B. ; Li, Huai ; Wang, Yue ; Kinnard, Lisa ; Freedman, Matthew T.
Author_Institution :
Center for Imaging Sci. & Inf. Syst., Georgetown Univ. Med. Center, Washington, DC, USA
Volume :
21
Issue :
2
fYear :
2002
Firstpage :
150
Lastpage :
158
Abstract :
A multiple circular path convolution neural network (MCPCNN) architecture specifically designed for the analysis of tumor and tumor-like structures has been constructed. We first divided each suspected tumor area into sectors and computed the defined mass features for each sector independently. These sector features were used on the input layer and were coordinated by convolution kernels of different sizes that propagated signals to the second layer in the neural network system. The convolution kernels were trained, as required, by presenting the training cases to the neural network. In this study, randomly selected mammograms were processed by a dual morphological enhancement technique. Radiodense areas were isolated and were delineated using a region growing algorithm. The boundary of each region of interest was then divided into 36 sectors using 36 equi-angular dividers radiated from the center of the region. A total of 144 Breast Imaging-Reporting and Data System-based features (i.e., four features per sector for 36 sectors) were computed as input values for the evaluation of this newly invented neural network system. The overall performance was 0.78-0.80 for the areas (A z) under the receiver operating characteristic curves using the conventional feed-forward neural network in the detection of mammographic masses. The performance was markedly improved with A z values ranging from 0.84 to 0.89 using the MCPCNN. This paper does not intend to claim the best mass detection system. Instead it reports a potentially better neural network structure for analyzing a set of the mass features defined by an investigator.
Keywords :
convolution; feature extraction; image segmentation; mammography; medical image processing; neural nets; computer-aided diagnosis; convolution kernels; dual morphological enhancement technique; feature extraction; mammographic masses detection; multiple circular path convolution neural network; randomly selected mammograms; receiver operating characteristic curves; region growing algorithm; sector features; sigmoid function; tumor structures; Biomedical imaging; Breast cancer; Convolution; Information systems; Kernel; Medical diagnostic imaging; Neoplasms; Neural networks; Radiology; Subcontracting; Breast Neoplasms; Databases, Factual; Feedback; Female; Humans; Image Interpretation, Computer-Assisted; Image Processing, Computer-Assisted; Mammography; Models, Biological; Models, Statistical; Neural Networks (Computer); Pattern Recognition, Automated; ROC Curve; Reproducibility of Results; Sensitivity and Specificity;
fLanguage :
English
Journal_Title :
Medical Imaging, IEEE Transactions on
Publisher :
ieee
ISSN :
0278-0062
Type :
jour
DOI :
10.1109/42.993133
Filename :
993133
Link To Document :
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