Title :
Effects of radiofrequency ablation on monoplasic action potentials
Author :
Merkely, Béla ; Vágó, Hajnalka ; Gellier, L. ; Zima, Endre ; Kiss, Orsolya ; Szucs, Andrea ; Graf, Marcus ; Lang, Volker ; Schaldach, Max
Author_Institution :
Dept. of Cardiovascular Surg., Semmelweis Univ., Budapest, Hungary
Abstract :
Reliable MAP (monophasic action potential) measurements were performed during RF delivery with a commercially available ablation system and fractally coated catheters based on an established mechanical design. The obtained results promise an important step forward in online monitoring of the MAP signals during ablation. They may help in the localization of the arrhythmogenic substrate (early and delayed after depolarization) and in the evaluation of RF ablation effect, which have to be investigated in further experimental and clinical studies
Keywords :
bioelectric potentials; biomedical electrodes; biomembrane transport; hyperthermia; radiofrequency heating; RF ablation; RF delivery time; arrhythmogenic substrate; bipolar electrode design; fractally coated ablation catheters; interface impedance; monophasic action potential; myocardial cells; spontaneous rhythm; transcatheter elimination; transmembrane action potentials; Analysis of variance; Biomedical engineering; Biomedical measurements; Catheters; Electrodes; Fractals; Myocardium; Performance evaluation; RF signals; Radio frequency;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
