DocumentCode
1268311
Title
Planar Wave Propagation Through a Tapered Flagellated Nanoswimmer
Author
Rathore, Jitendra Singh ; Majumdar, Rwitajit ; Sharma, Niti Nipun
Author_Institution
Dept. of Mech. Eng., Birla Inst. of Technol. & Sci., Pilani, India
Volume
11
Issue
6
fYear
2012
Firstpage
1117
Lastpage
1121
Abstract
Nanoswimmers are important because of their potential use for the purpose of drug delivery, monitoring, and diagnostics for in vivo biomedical application. They mimic microorganisms and mostly modeled as propelled by beating or rotating flagella. In the vast literature available on modeling of flagellar propulsion, the flagellum is considered constant diameter where as the actual microorganism have tapered flagella. The present study deals with the modeling and simulation of planar wave propagation through a tapered flagellum of a nanoswimmer for a given taper ratio. The performance parameters of velocity and efficiency are compared with the uniform diameter case. Taper diameter modeling of flagellum gives a superior performance by indicating higher velocity and efficiency. The parametric study with respect to the elasticity of the material of the flagellum and its beat frequency is also analyzed. The performance increases with increasing frequency, and the maxima for both velocity and efficiency of the tapered case is reached at a lower elasticity than the uniform case. The maximum efficiency of the taper case is almost double the maxima of the uniform diameter flagellum. The observations in the present study can be utilized while designing artificial flagellum for nanoswimmers and suggests that the tapered flagellum would be a more optimal choice of design as compared to the uniform one of the same volume.
Keywords
biomechanics; drug delivery systems; elasticity; microorganisms; nanobiotechnology; artificial flagellum; beat frequency; drug delivery; elasticity; flagellar propulsion modeling; in vivo biomedical application; microorganisms; planar wave propagation modeling; planar wave propagation simulation; taper case efficiency; taper diameter modeling; taper ratio; tapered flagellated nanoswimmer; uniform diameter flagellum; Drag; Elasticity; Force; Mathematical model; Microorganisms; Propulsion; Shape; Biological system modeling; elasticity; nanobioscience; propulsion;
fLanguage
English
Journal_Title
Nanotechnology, IEEE Transactions on
Publisher
ieee
ISSN
1536-125X
Type
jour
DOI
10.1109/TNANO.2012.2214230
Filename
6275495
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