• DocumentCode
    1288238
  • Title

    Surface plasmon resonance imaging for biosensing

  • Author

    Paul, Sudipta ; Vadgama, Pankaj ; Ray, A.K.

  • Author_Institution
    Sch. of Eng. & Mater. Sci., Queen Mary, Univ. of London, London, UK
  • Volume
    3
  • Issue
    3
  • fYear
    2009
  • fDate
    9/1/2009 12:00:00 AM
  • Firstpage
    71
  • Lastpage
    80
  • Abstract
    Surface plasmon resonance imaging (SPRI) is a useful tool for the study of surface biomolecular interactions allowing for label-free detection and elegant instrumentation. SPRI imaging system is described in this review with an emphasis on recent applications with examples of different biological interactions and high throughput analysis. Signal amplification in SPRI using nanoparticle and waveguide-based optical coupling is introduced. Finally the detection sensitivity of the SPRI system is examined in terms of other competitive methods.
  • Keywords
    bio-optics; biological techniques; biosensors; molecular biophysics; nanoparticles; nanotechnology; surface plasmon resonance; SPRI signal amplification; biosensor; detection sensitivity; label-free detection; nanoparticle-based optical coupling; surface biomolecular interaction; surface plasmon resonance imaging; waveguide-based optical coupling;
  • fLanguage
    English
  • Journal_Title
    Nanobiotechnology, IET
  • Publisher
    iet
  • ISSN
    1751-8741
  • Type

    jour

  • DOI
    10.1049/iet-nbt.2008.0012
  • Filename
    5196651