DocumentCode
1288238
Title
Surface plasmon resonance imaging for biosensing
Author
Paul, Sudipta ; Vadgama, Pankaj ; Ray, A.K.
Author_Institution
Sch. of Eng. & Mater. Sci., Queen Mary, Univ. of London, London, UK
Volume
3
Issue
3
fYear
2009
fDate
9/1/2009 12:00:00 AM
Firstpage
71
Lastpage
80
Abstract
Surface plasmon resonance imaging (SPRI) is a useful tool for the study of surface biomolecular interactions allowing for label-free detection and elegant instrumentation. SPRI imaging system is described in this review with an emphasis on recent applications with examples of different biological interactions and high throughput analysis. Signal amplification in SPRI using nanoparticle and waveguide-based optical coupling is introduced. Finally the detection sensitivity of the SPRI system is examined in terms of other competitive methods.
Keywords
bio-optics; biological techniques; biosensors; molecular biophysics; nanoparticles; nanotechnology; surface plasmon resonance; SPRI signal amplification; biosensor; detection sensitivity; label-free detection; nanoparticle-based optical coupling; surface biomolecular interaction; surface plasmon resonance imaging; waveguide-based optical coupling;
fLanguage
English
Journal_Title
Nanobiotechnology, IET
Publisher
iet
ISSN
1751-8741
Type
jour
DOI
10.1049/iet-nbt.2008.0012
Filename
5196651
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