Feasibility of shear wave elastography for plaque characterization

Author

Widman, Erik ; Maksuti, Elira ; Larsson, Daniel ; Urban, Matthew ; Caidahl, Kenneth ; Bjallmark, Anna ; Larsson, Mats

Author_Institution

Dept. of Med. Eng., KTH R. Inst. of Technol., Stockholm, Sweden

fYear

2014

fDate

3-6 Sept. 2014

Firstpage

1818

Lastpage

1821

Abstract

Determining plaque vulnerability is critical when selecting the most suitable treatment for patients with atherosclerotic plaque in the common carotid artery and quantitative characterization methods are needed. In this study, shear wave elastography (SWE) was used to characterize soft plaque mimicking inclusions in three atherosclerotic arterial phantoms by using phase velocity analysis in a static environment. The results were validated with axial tensile mechanical testing (MT). SWE measured a mean shear modulus of 5.8 ± 0.3 kPa and 25.0 ± 1.2 kPa versus 3.0 kPa and 30.0 kPa measured by mechanical testing in the soft plaques and phantom walls respectively. The results show good agreement between MT and SWE for both the plaque and phantom wall.

Keywords

elastic waves; shear modulus; tensile testing; SWE; atherosclerotic arterial phantoms; atherosclerotic plaque; feasibility; phantom wall; phase velocity analysis; plaque mimicking; plaque vulnerability; shear modulus; shear wave elastography; tensile mechanical testing; Acoustics; Carotid arteries; Mechanical variables measurement; Phantoms; Testing; Ultrasonic imaging; Carotid Artery; Mechanical Testing; Phase Velocity; Plaque Characterization; Shear Wave Elastography;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium (IUS), 2014 IEEE International

Conference_Location

Chicago, IL

Type

conf

DOI

10.1109/ULTSYM.2014.0451

Filename

6932274