DocumentCode
1299411
Title
Regular Networks Can be Uniquely Constructed from Their Trees
Author
Willson, Stephen J.
Author_Institution
Dept. of Math., Iowa State Univ., Ames, IA, USA
Volume
8
Issue
3
fYear
2011
Firstpage
785
Lastpage
796
Abstract
A rooted acyclic digraph N with labeled leaves displays a tree T when there exists a way to select a unique parent of each hybrid vertex resulting in the tree T. Let Tr(N) denote the set of all trees displayed by the network N. In general, there may be many other networks M, such that Tr(M) = Tr(N). A network is regular if it is isomorphic with its cover digraph. If N is regular and D is a collection of trees displayed by N, this paper studies some procedures to try to reconstruct N given D. If the input is D = Tr(N), one procedure is described, which will reconstruct N. Hence, if N and M are regular networks and Tr(N) = Tr(M), it follows that N = M, proving that a regular network is uniquely determined by its displayed trees. If D is a (usually very much smaller) collection of displayed trees that satisfies certain hypotheses, modifications of the procedure will still reconstruct N given D.
Keywords
genetics; genomics; molecular biophysics; trees (mathematics); acyclic digraph; gene mutation; gene trees; hybrid vertex; phylogenetic tree; regular networks; Bioinformatics; Computational biology; Construction industry; Genetics; Pediatrics; Phylogeny; Phylogeny; hybrid.; network; phylogenetic; regular; tree; Cluster Analysis; Computational Biology; Evolution, Molecular; Genes, Fungal; Models, Genetic; Phylogeny;
fLanguage
English
Journal_Title
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
Publisher
ieee
ISSN
1545-5963
Type
jour
DOI
10.1109/TCBB.2010.69
Filename
5551119
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