Title :
A 64 Channel Programmable Closed-Loop Neurostimulator With 8 Channel Neural Amplifier and Logarithmic ADC
Author :
Lee, Jongwoo ; Rhew, Hyo-Gyuem ; Kipke, Daryl R. ; Flynn, Michael P.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
This paper describes a neurostimulation IC for use in advanced closed-loop neurostimulation applications, such as deep brain stimulation (DBS) for treatment and research of neurological disorders including Parkinson´s disease. This system senses and filters neural activity with eight pre-amplifiers, a 200 kS/s 8-bit log ADC and digital filters and incorporates 64 programmable current-stimulation channels. The entire device, implemented in 0.18 μm CMOS, occupies 2.7 mm2 and consumes 89 μW in normal operation mode and 271 μW in configuration mode from a 1.8 V supply.
Keywords :
CMOS digital integrated circuits; analogue-digital conversion; biomedical electronics; digital filters; neural chips; preamplifiers; CMOS technology; Parkinson disease; deep brain stimulation; digital filters; logarithmic ADC; neural amplifier; neurological disorders; neurostimulation IC; power 271 muW; power 89 muW; preamplifiers; programmable closed-loop neurostimulator; programmable current-stimulation channels; size 0.18 mum; voltage 1.8 V; word length 8 bit; Gain; Multiplexing; Noise; Parkinson´s disease; Pipelines; Prototypes; System-on-a-chip; Log ADC; neural recording; neurostimulation;
Journal_Title :
Solid-State Circuits, IEEE Journal of
DOI :
10.1109/JSSC.2010.2052403
