Title :
Engineering the Human Genome Project
Author :
Beugelsdijk, Tony J.
Author_Institution :
Los Alamos Nat. Lab., NM, USA
Abstract :
The Human Genome Initiative, a worldwide research effort to analyze the structure of human deoxyribonucleic acid (DNA) and determine the location of all human genes, is discussed. The nature of the task is described, and the technologies needed to construct ´libraries´ of overlapping clones of DNA fragments are examined. DNA sequencing methods and technologies are also discussed. The role that the engineer could play in supporting the project by advances in instrumentation is briefly discussed.<>
Keywords :
DNA; biological techniques and instruments; molecular biophysics; DNA; Human Genome Initiative; genes; human deoxyribonucleic acid; instrumentation; molecular biophysics; overlapping clones; research; sequencing methods; Biochemistry; Bioinformatics; Biological cells; Cells (biology); Cloning; DNA; Genomics; Humans; Libraries; Sequences;
Journal_Title :
Potentials, IEEE
