THz Chemical Imaging for Biological Applications

Author

Ajito, Katsuhiro ; Ueno, Yuko

Author_Institution

Microsyst. Integration Labs., NTT Cor poration, Atsugi, Japan

Volume

1

Issue

1

fYear

2011

Firstpage

293

Lastpage

300

Abstract

THz spectroscopy is advantageous in analytical chemistry because it can detect and identify intermolecular interactions in chemical compounds, such as hydrogen bonds and hydrations, and molecular networks. Recent advances in THz components, such as ultrashort pulsed lasers and photoconductive antennas, have improved the sensitivity of THz time-domain (TDS) spectroscopy and have made the THz chemical imaging possible. THz chemical imaging can reveal hydrogen bond distributions and will be a very powerful tool in biology, pharmacology, and life sciences. THz-TDS is also promising for the quantitative chemical analysis and detection of molecules and clusters in nanospace and ice.

Keywords

antennas; biological techniques; high-speed optical techniques; molecular biophysics; photoconducting devices; spectrochemical analysis; terahertz spectroscopy; THz chemical imaging; THz components; THz spectroscopy; THz time domain spectroscopy; analytical chemistry; biological applications; hydrations; hydrogen bond distributions; hydrogen bonds; intermolecular interactions; molecular networks; photoconductive antennas; ultrashort pulsed lasers; Absorption; Amino acids; Chemicals; Crystals; Imaging; Spectroscopy; Cancer diagnosis; hydrogen bonds; molecular clusters; molecular interactions; molecular networks; quantitative chemical analysis; terahertz chemical imaging;

fLanguage

English

Journal_Title

Terahertz Science and Technology, IEEE Transactions on

Publisher

ieee

ISSN

2156-342X

Type

jour

DOI

10.1109/TTHZ.2011.2159562

Filename

6005325