New Daily Detector Uniformity Quality Control Methodology for Cardiac SPECT Using Solid-State Detectors

Detector non-uniformity can potentially introduce detectable artifacts into SPECT images. The degree of the non-uniformity and the extent and position of the non-uniform area on the detector surface determine the position and severity of the introduced artifacts. The commonly used daily uniformity quality control (QC) procedure follows the NEMA methodology but acquires fewer counts than the latter specifies. It has three major drawbacks: (1) it does not report the locations and extent of the non-uniform areas on the detector surface; (2) it may report a non-uniformity value that is lower than the true value due to the use of a 9-point filter, and it makes the reported non-uniformity value vary with the extent of the non-uniform area. These two drawbacks are inherited from the NEMA methodology. The third drawback is that the noise due to the relatively low counts collected in daily uniformity QC does not allow the measurement of certain degrees of non-uniformity with adequate statistical significance, yet such non-uniformity can potentially introduce observable artifacts. In this work we propose a new methodology for daily uniformity QC for cardiac SPECT imaging using solid-state detectors. The new QC procedure (1) reports the locations and extents of the non-uniform areas of the detectors and (2) can catch some detectors that pass the NEMA-based daily uniformity QC but are non-uniform enough to introduce detectable artifacts.