Title :
Autonomic cardiovascular modulation
Author :
Tobaldini, Eleonora ; Montano, Nicola ; Wei, Shun-guang ; Zhang, Zhi-hua ; Francis, Joseph ; Weiss, Robert M. ; Casali, Karina R. ; Felder, Robert B. ; Porta, Alberto
Author_Institution :
Univ. of Milan, Milan, Italy
Abstract :
The aim of the study was twofold: first, to validate symbolic analysis as a tool capable of assessing autonomic cardiovascular regulation in rats and, second, to investigate neural cardiovascular regulation during the progression of ischemic induced chronic heart failure (CHF) in two groups of rats, a control group and a group treated with chronic administration of the mineralocorticoid receptor antagonist SP, a drug playing a protective role over cardiovascular regulation.
Keywords :
biomedical measurement; cardiovascular system; diseases; medical signal detection; statistical analysis; autonomic cardiovascular modulation; chronic heart failure; mineralocorticoid receptor antagonist; neural cardiovascular regulation; Analytical models; Animals; Blood pressure; Cardiology; Cardiovascular diseases; Heart rate; Myocardium; Pulse modulation; Rats; Spectral analysis; Analysis of Variance; Animals; Autonomic Nervous System; Blood Pressure; Chronic Disease; Computer Simulation; Disease Models, Animal; Heart Failure; Humans; Nonlinear Dynamics; Pulse; Rats; Rats, Sprague-Dawley; Receptors, Mineralocorticoid; Reproducibility of Results; Signal Processing, Computer-Assisted; Spironolactone; Statistics, Nonparametric;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2009.934620
