• DocumentCode
    1335459
  • Title

    Single-Ion Channel Recordings on Quartz Substrates

  • Author

    Stava, Eric ; Yu, Minrui ; Shin, Hyun Cheol ; Blick, Robert H.

  • Author_Institution
    Dept. of Electr. & Comput. Eng., Univ. of Wisconsin-Madison, Madison, WI, USA
  • Volume
    9
  • Issue
    4
  • fYear
    2010
  • Firstpage
    307
  • Lastpage
    309
  • Abstract
    We show that a single-crystal quartz substrate provides a working platform for ion channel research. Single-crystal quartz is piezoelectric, so it can be nanomechanically actuated to perform precise membrane deformations. This, along with its superior noise properties, makes single-crystal quartz ideal for analyzing mechanosensitive ion channels.
  • Keywords
    bioelectric phenomena; biomembrane transport; nanobiotechnology; nanomechanics; piezoelectric materials; quartz; mechanosensitive ion channel; membrane deformations; nanomechanical actuation; piezoelectric materials; single-crystal quartz substrate; single-ion channel recordings; Apertures; Biomembranes; Environmental factors; Lipidomics; Piezoelectric materials; Substrates; Biomembranes; ion channels; piezoelectric; planar patch clamping; quartz; Biophysical Phenomena; Biophysics; Ion Channels; Lipid Bilayers; Quartz;
  • fLanguage
    English
  • Journal_Title
    NanoBioscience, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    1536-1241
  • Type

    jour

  • DOI
    10.1109/TNB.2010.2076830
  • Filename
    5585772
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=1335459