Title :
PC-based noninvasive measurement of the autonomic nervous system. Detecting the onset of diabetic autonomic neuropathy
Author :
Pruna, S. ; Dumitrescu, A.
Author_Institution :
Soc. for Clinical Eng. & Med. Comput.
Abstract :
The IBM PC-based system and experimental results presented here describe a new approach to recording electrophysiological signals associated with the autonomic nervous system, and the detection of the changes in electrophysiological signals due to onset of diabetic autonomic neuropathy. The authors have shown that the skin sympathetic sudomotor activity has much lower amplitude due to the functional state of the ANS caused by the diabetic neuropathy. The skin transient pulse blood (STPB) amplitude over many sweeps is statistically correlated with the laser Doppler flowmetry amplitude, but the photoplethysmographic technique is less expensive. Spectral analysis of STPB in the frequency range 0.5-2 Hz enables the separate assessment of parasympathetic and sympathetic activities and the rapid detection of cardiac autonomic neuropathy
Keywords :
bioelectric potentials; biomedical equipment; biomedical measurement; computerised instrumentation; medical diagnostic computing; microcomputer applications; neurophysiology; patient diagnosis; skin; spectral analysis; 0.5 to 2 Hz; PC-based noninvasive measurement; autonomic nervous system; cardiac autonomic neuropathy; chronic disease; diabetic autonomic neuropathy onset detection; electrophysiological signals recording; laser Doppler flowmetry amplitude; medical instrumentation; nervous system functional state; photoplethysmographic technique; skin transient pulse blood amplitude; Attenuation measurement; Autonomic nervous system; Diabetes; Diseases; Impedance; Medical tests; Noninvasive treatment; Skin; System testing; Voltage;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
