Towards a portable point-of-use blood analysis with EIS technique device

In this paper first approach to a compact system for point-of-use primarily blood characteristics analysis by means of an EIS (Electrochemical Impedance Spectroscopy) experience is described. This is based on a custom electronic instrumentation, post processing software and a commercial three electrodes gold sensor. The designed electronic is based on a potentiostat instrumentation supported by a real time platform connected to a remote computer, which allows the instrumentation control, real time monitoring data and its posterior resultant analysis. Moreover, the whole system has been characterized and validated using different sensors and biocompatible materials. The study consists on a complete EIS experience in order to get a full spectrum analysis of impedance behavior in terms of magnitude and phase. As a result, we were able to detect impedance with an average error of less than 3% and a SNR rejection of -40 dB in a frequency working range of 10 Hz to 100 kHz. This integrated approach pushes forward the development of truly autonomous point-of-care devices relying on impedance spectrometry detection.