DocumentCode
1364215
Title
Realistic Analytical Phantoms for Parallel Magnetic Resonance Imaging
Author
Guerquin-Kern, M. ; Lejeune, L. ; Pruessmann, K.P. ; Unser, Michael
Author_Institution
Biomed. Imaging Group, Ecole Polytech. Fed. de Lausanne, Lausanne, Switzerland
Volume
31
Issue
3
fYear
2012
fDate
3/1/2012 12:00:00 AM
Firstpage
626
Lastpage
636
Abstract
The quantitative validation of reconstruction algorithms requires reliable data. Rasterized simulations are popular but they are tainted by an aliasing component that impacts the assessment of the performance of reconstruction. We introduce analytical simulation tools that are suited to parallel magnetic resonance imaging and allow one to build realistic phantoms. The proposed phantoms are composed of ellipses and regions with piecewise-polynomial boundaries, including spline contours, Bézier contours, and polygons. In addition, they take the channel sensitivity into account, for which we investigate two possible models. Our analytical formulations provide well-defined data in both the spatial and k-space domains. Our main contribution is the closed-form determination of the Fourier transforms that are involved. Experiments validate the proposed implementation. In a typical parallel magnetic resonance imaging reconstruction experiment, we quantify the bias in the overly optimistic results obtained with rasterized simulations-the inverse-crime situation. We provide a package that implements the different simulations and provide tools to guide the design of realistic phantoms.
Keywords
Fourier transforms; biomedical MRI; image reconstruction; medical image processing; phantoms; piecewise polynomial techniques; Bézier contours; Fourier transforms; aliasing component; analytical simulation tools; channel sensitivity; ellipses; inverse-crime situation; parallel magnetic resonance imaging reconstruction experiment; piecewise-polynomial boundaries; polygons; quantitative validation; rasterized simulations; realistic analytical phantoms; reconstruction algorithms; spline contours; Analytical models; Coils; Computational modeling; Magnetic resonance imaging; Phantoms; Polynomials; Sensitivity; Fourier analytical simulation; Shepp–Logan; inverse crime; magnetic resonance imaging (MRI); Algorithms; Brain; Computer Simulation; Fourier Analysis; Humans; Magnetic Resonance Imaging; Models, Biological; Phantoms, Imaging; Reproducibility of Results;
fLanguage
English
Journal_Title
Medical Imaging, IEEE Transactions on
Publisher
ieee
ISSN
0278-0062
Type
jour
DOI
10.1109/TMI.2011.2174158
Filename
6062681
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