• DocumentCode
    1364215
  • Title

    Realistic Analytical Phantoms for Parallel Magnetic Resonance Imaging

  • Author

    Guerquin-Kern, M. ; Lejeune, L. ; Pruessmann, K.P. ; Unser, Michael

  • Author_Institution
    Biomed. Imaging Group, Ecole Polytech. Fed. de Lausanne, Lausanne, Switzerland
  • Volume
    31
  • Issue
    3
  • fYear
    2012
  • fDate
    3/1/2012 12:00:00 AM
  • Firstpage
    626
  • Lastpage
    636
  • Abstract
    The quantitative validation of reconstruction algorithms requires reliable data. Rasterized simulations are popular but they are tainted by an aliasing component that impacts the assessment of the performance of reconstruction. We introduce analytical simulation tools that are suited to parallel magnetic resonance imaging and allow one to build realistic phantoms. The proposed phantoms are composed of ellipses and regions with piecewise-polynomial boundaries, including spline contours, Bézier contours, and polygons. In addition, they take the channel sensitivity into account, for which we investigate two possible models. Our analytical formulations provide well-defined data in both the spatial and k-space domains. Our main contribution is the closed-form determination of the Fourier transforms that are involved. Experiments validate the proposed implementation. In a typical parallel magnetic resonance imaging reconstruction experiment, we quantify the bias in the overly optimistic results obtained with rasterized simulations-the inverse-crime situation. We provide a package that implements the different simulations and provide tools to guide the design of realistic phantoms.
  • Keywords
    Fourier transforms; biomedical MRI; image reconstruction; medical image processing; phantoms; piecewise polynomial techniques; Bézier contours; Fourier transforms; aliasing component; analytical simulation tools; channel sensitivity; ellipses; inverse-crime situation; parallel magnetic resonance imaging reconstruction experiment; piecewise-polynomial boundaries; polygons; quantitative validation; rasterized simulations; realistic analytical phantoms; reconstruction algorithms; spline contours; Analytical models; Coils; Computational modeling; Magnetic resonance imaging; Phantoms; Polynomials; Sensitivity; Fourier analytical simulation; Shepp–Logan; inverse crime; magnetic resonance imaging (MRI); Algorithms; Brain; Computer Simulation; Fourier Analysis; Humans; Magnetic Resonance Imaging; Models, Biological; Phantoms, Imaging; Reproducibility of Results;
  • fLanguage
    English
  • Journal_Title
    Medical Imaging, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0278-0062
  • Type

    jour

  • DOI
    10.1109/TMI.2011.2174158
  • Filename
    6062681