• DocumentCode
    1368237
  • Title

    A Novel Cell Irradiation System Using 90 ^{\\circ} -Scattering Technique

  • Author

    Cho, I.C. ; Weng, M.F. ; Wu, J.M. ; Chiang, S.Y. ; Chou, W.T. ; Niu, H. ; Hsu, C.-H.

  • Author_Institution
    Dept. of Biomed. Eng. & Environ. Sci., Nat. Tsing Hua Univ., Hsinchu, Taiwan
  • Volume
    58
  • Issue
    1
  • fYear
    2011
  • Firstpage
    95
  • Lastpage
    98
  • Abstract
    A novel cell irradiation system was developed for use with the HVEE Van de Graaff accelerator at the National Tsing Hua University. A 90°-scattering technique using an Au foil was designed, in which charged particles were directed from horizontal to vertical irradiation. Beam performance was tested with a silicon detector and a CR-39 nuclear track detector. The HeLa cells were irradiated with 2-MeV alpha particles and the formation of giant cells was observed. The result showed that this system provides a convenient way of generating a vertical particle beam and a cell-supporting chamber, thereby allowing a suitable cell growth condition during irradiation. Furthermore, establishment of such a system is more convenient and economical than the alternatives.
  • Keywords
    alpha-particle effects; biological effects of radiation; ion beam applications; position sensitive particle detectors; silicon radiation detectors; van de Graaff accelerators; 90°-scattering technique; Au foil; CR-39 nuclear track detector; HVEE Van de Graaff accelerator; HeLa cells; alpha particles; cell growth; cell irradiation system; cell-supporting chamber; charged particles; electron volt energy 2 MeV; giant cells; ion beam applications; silicon detector; vertical particle beam; Accelerator; biological effect of radiation; ion beam applications;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.2010.2087036
  • Filename
    5618602