Improvement of oxidative stability of conjugated linolenic acid by complexation with Β-cyclodextrin

Although the outstanding functions of conjugated linolenic acid (CLN) related to human health have gained increased popularity, there are limited applications about them in the daily life due to oxidation unstability. Here, β-cyclodextrin (β-CD) was applied as a carrier for CLN encapsulation. High-resolution transmission electron microscopy indicated that the CLN-loaded β-CD were nanoflakes, with about 50 nm in thickness. Fourier transform infrared spectrograph and UV-vis adsorption conformed that CLN was successfully loaded on β-CD with 97.8% of encapsulation efficiency and 10.5% of CLN loading. What´s more important was that the oxidation stability of CLN was sig nificantly improved by β-CD. It was found that only 35% of CLN oxidised in 280 h, whereas free CLN was oxidised completely at the same condition.