DocumentCode :
1373514
Title :
Graph Formations of Partial-Order Multiple-Sequence Alignments Using Nanoscale, Microscale, and Multiscale Reconfigurable Meshes
Author :
Eshaghian-Wilner, M.M. ; Ling Lau ; Navab, S. ; Shen, Dayong
Author_Institution :
Electr. Eng. Dept., Univ. of California, Los Angeles, CA, USA
Volume :
8
Issue :
3
fYear :
2009
Firstpage :
201
Lastpage :
209
Abstract :
In this paper, we show how to form partial-order multiple-sequence alignment graphs on two types of reconfigurable mesh architectures. The first reconfigurable mesh is a standard microscale that uses electrical interconnects, while the second type of reconfigurable mesh can be implemented at a nanoscale level and employs spin waves for interconnectivity. We consider graph formations for two cases. In one case, the number of distinct variables in the data sequences is constant. In the other case, it can be as much as O(N). We show that given O(N) aligned sequences of length L, we can combine the sequences to form a graph in O(1) time, using either architecture if there is a constant number of distinct variables in the sequence. Otherwise, it will take O(1) time if we use the spin-wave model and O(N) time if we use the standard very large scale integration version.
Keywords :
bioinformatics; coprocessors; graph theory; molecular biophysics; parallel algorithms; reconfigurable architectures; electrical interconnects; interconnectivity; microscale reconfigurable mesh; multiscale reconfigurable mesh; nanoscale reconfigurable mesh; partial order multiple sequence alignment graph formation; reconfigurable mesh architecture; spin waves; spin-wave model; Bioinformatics; Biological system modeling; Computational biology; Computer architecture; DNA; Genomics; Hardware; Humans; Nanobioscience; Sequences; Parallel computing; partial-order multiple sequence alignment; reconfigurable mesh; spin wave; Algorithms; Base Sequence; DNA; Molecular Sequence Data; Nanotechnology; Numerical Analysis, Computer-Assisted; Sequence Alignment; Sequence Analysis, DNA;
fLanguage :
English
Journal_Title :
NanoBioscience, IEEE Transactions on
Publisher :
ieee
ISSN :
1536-1241
Type :
jour
DOI :
10.1109/TNB.2009.2029230
Filename :
5371780
Link To Document :
بازگشت