Title :
Evaluation of a Novel Electrochemical Detection Method for Chlamydia trachomatis : Application for Point-of-Care Diagnostics
Author :
Pearce, David M. ; Shenton, Daniel P. ; Holden, Jeffrey ; Gaydos, Charlotte A.
Author_Institution :
Atlas Genetics Ltd., Trowbridge, UK
fDate :
3/1/2011 12:00:00 AM
Abstract :
Atlas Genetics has developed a point-of-care device for Chlamydia trachomatis utilizing a novel electrochemical detection principle. The assay has a time-to-result of less than 25 min. An independent preclinical validation study using 306 pretyped clinical samples determined a clinical sensitivity of 98.1% and specificity of 98.0%.
Keywords :
diseases; electrochemical sensors; microorganisms; patient diagnosis; Atlas Genetics; Chlamydia trachomatis; clinical sensitivity; electrochemical detection method; point-of-care diagnostics; specificity; DNA; Diseases; Oxidation; Probes; Sensitivity; Testing; Chlamydia; electrochemistry; infectious disease; point-of-care; Chlamydia Infections; Chlamydia trachomatis; Electrochemical Techniques; Humans; Microfluidic Analytical Techniques; Point-of-Care Systems; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
DOI :
10.1109/TBME.2010.2095851
