Title :
CMOS-based high-speed nanopore recording: Signals and systems
Author :
Magierowski, S. ; Islam, Syed Zahidul ; Huang, Yi-Pai ; Ghafar-Zadeh, Ebrahim
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., York Univ., Toronto, ON, Canada
Abstract :
This paper considers the potential of CMOS-based nanopore measurement systems for high-speed molecular recording and DNA sequencing in particular. As such it approximates the signal fidelity limitations of a CMOS-based nanopore readout channel and discusses the means by which throughput could be increased through the use of a parallel CMOS readout system.
Keywords :
CMOS integrated circuits; DNA; biological techniques; biology computing; molecular biophysics; signal processing; CMOS-based high-speed nanopore recording; CMOS-based nanopore measurement systems; CMOS-based nanopore readout channel; DNA sequencing; high-speed molecular recording; parallel CMOS readout system; signal fidelity limitations; CMOS integrated circuits; Current measurement; DNA; Nanobioscience; Sequential analysis; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6943901
