Title :
Optimized methodology for neonatal diffusion tensor imaging processing and study-specific template construction
Author :
Evangelou, Iordanis E. ; Serag, Ahmed ; Bouyssi-Kobar, Marine ; Plessis, Adre J. Du ; Limperopoulos, Catherine
Author_Institution :
Div. of Diagnostic Imaging & Radiol., Adv. Pediatric Brain Imaging Lab., Washington, DC, USA
Abstract :
Diffusion tensor imaging (DTI) has been widely used to study cerebral white matter microstructure in vivo. There is a plethora of open source tools available to perform pre-processing, analysis and template or atlas construction, however very few have been optimized for use with neonatal DTI data. Here we present a fully automated modular pipeline optimized for neonatal DTI data and the construction of study-specific tensor templates. We compare our methodology to an existing one. It is anticipated that the construction of population or study-specific templates will facilitate better group comparisons of neonatal populations both in health and disease.
Keywords :
biodiffusion; biomedical MRI; brain; medical image processing; paediatrics; atlas construction; cerebral white matter microstructure; neonatal DTI data; neonatal diffusion tensor imaging processing; open source tools; study-specific tensor template construction; Diffusion tensor imaging; Diseases; Measurement; Pediatrics; Tensile stress;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6944098