Title :
Automated feedback control of body temperature for small animal studies with MR microscopy
Author :
Qiu, Hui H. ; Cofer, Gary P. ; Hedlund, Laurence W. ; Johnson, G. Allan
Author_Institution :
Dept. of Radiol., Duke Univ. Med. Center, Durham, NC, USA
Abstract :
A temperature control system consisting of a thermistor, signal processor, and computer algorithm was developed for magnetic resonance (MR) microscopy of small live animals. With control of body temperature within ±0.2°C of the set point, heart rate is stabilized and, in turn, repetition time (TR) during cardiac-gated studies is less variable. Thus, image quality and resolution are improved.
Keywords :
biocontrol; biological NMR; biological techniques; biothermics; computerised control; feedback; temperature control; thermistors; MR microscopy; automated feedback control; biological research instrumentation; body temperature; cardiac-gated studies; computer algorithm; heart rate stabilization; image quality; image resolution; repetition time; set point; signal processor; small animal studies; temperature control system; Animals; Automatic control; Feedback control; Magnetic force microscopy; Magnetic resonance; Signal processing; Signal processing algorithms; Temperature control; Thermal variables control; Thermistors; Animals; Body Temperature; Equipment Design; Feedback; Ferrets; Guinea Pigs; Magnetic Resonance Imaging; Mice; Microscopy; Models, Biological; Monitoring, Physiologic; Rats; Respiration, Artificial; Signal Processing, Computer-Assisted; Thermometers;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
