A novel device to preserve intestinal tissue Ex-Vivo by cold peristaltic perfusion

Author

Narayan, Raja R. ; Pancer, Natalie E. ; Loeb, Brian W. ; Oki, Kristi ; Crouch, Andrew ; Backus, Spencer ; Chauhan, Yusuf ; Patron-Lozano, Roger ; Rodriguez-Davalos, Manuel I. ; Geibel, John P. ; Fan, Richard E. ; Zinter, Joseph P.

Author_Institution

Sch. of Public Health, Yale Univ., New Haven, CT, USA

fYear

2014

fDate

26-30 Aug. 2014

Firstpage

3118

Lastpage

3121

Abstract

In the past two decades, much advancement has been made in the area of organ procurement and preservation for the transplant of kidneys, livers, and lungs. However, small intestine preservation remains unchanged. We propose a new preservation system for intestinal grafts that has the potential to increase the viability of the organ during transport. When experimented with porcine intestine, our device resulted in superior tissue quality than tissue in standard of care.

Keywords

biological organs; biological tissues; biomedical engineering; haemorheology; cold peristaltic perfusion; intestinal grafts; intestinal tissue; kidneys; livers; lungs; organ preservation; organ procurement; organ viability; porcine intestine; small intestine preservation; tissue quality; Educational institutions; Ice; Intestines; Procurement; Pumps; Standards; Surgery;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE

Conference_Location

Chicago, IL

ISSN

1557-170X

Type

conf

DOI

10.1109/EMBC.2014.6944283

Filename

6944283