Title :
Techniques and applications of dynamic contrast enhanced magnetic resonance imaging in cancer
Author :
Barnes, Sean L. ; Whisenant, Jennifer G. ; Xia Li ; Yankeelov, Thomas E.
Author_Institution :
Dept. of Radiol. & Radiol. Sci., Vanderbilt Univ. Inst. of Imaging Sci. (VUIIS), Nashville, TN, USA
Abstract :
We first discuss several key technical issues associated with quantitative dynamic contrast enhanced magnetic resonance imaging (DCE-MRI), and then provide examples of DCE-MRI in oncology. In particular, we examine the importance of both active and passive delivery of the contrast agent to the tissue under investigation, and repeatability/reproducibility in DCE-MRI studies. We then discuss examples of how DCE-MRI can assist in assessing and predicting therapeutic response in the neoadjuvant setting.
Keywords :
biomedical MRI; cancer; tracers; tumours; DCE magnetic resonance imaging; DCE-MRI; active contrast agent delivery; cancer; dynamic contrast enhanced MRI; oncology; passive contrast agent delivery; therapeutic response prediction; Analytical models; Breast cancer; Magnetic resonance imaging; Medical treatment; Tumors;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6944566
