Title :
Alveolar air Volatile Organic Compound extractor for clinical breath sampling
Author :
de Silva, Geethanga ; Beyette, Fred R.
Author_Institution :
Dept. of Electr. Eng. & Comput. Syst., Univ. of Cincinnati, Cincinnati, OH, USA
Abstract :
Alveolar air Volatile Organic Compound (VOC) extractor is a handheld breath-sampling device for clinical breath analysis. The device consists two main components: (1) An alveolar air separator, (2) A VOC extractor. The alveolar air separator splits exhaled air based on total exhaled air volume directing alveolar air towards the VOC extractor and dead space air to into an exhaust channel. The VOC extractor collects the VOCs from alveolar air into a modified Sold Phase Micro Extraction (SPME) filament. Feasibility of using the SPME filament to collect a quantifiable breath sample directly from exhaled breath is experimentally validated. Exhaled breath acetone is quantified using alveolar air VOC extractor and a GC/MS system.
Keywords :
biomedical equipment; biomedical measurement; organic compounds; pneumodynamics; SPME filament; VOC extractor; alveolar air separator; alveolar air volatile organic compound extractor; clinical breath analysis; clinical breath sampling; dead space air; exhaled breath acetone; handheld breath-sampling device; sold phase micro extraction filament; total exhaled air volume; Actuators; Calibration; Containers; Needles; Particle separators; Standards; Volatile organic compounds;
Conference_Titel :
Engineering in Medicine and Biology Society (EMBC), 2014 36th Annual International Conference of the IEEE
Conference_Location :
Chicago, IL
DOI :
10.1109/EMBC.2014.6944839
