Title :
Discovering Inhibition Pathways for Protein Kinases
Author :
Chen, Qingfeng ; Chen, Yi-Ping Phoebe
Abstract :
The inhibition of protein kinase activity can cause disease. The authors present a method for investigating inhibitive regulatory correlations between kinase isoforms and physical factors.
Keywords :
biology; proteins; discovering inhibition pathways; kinase isoforms; physical factors; protein kinases; regulatory correlations; Artificial neural networks; Intelligent systems; Itemsets; Muscles; Proteins; activation; data mining; inhibition; negative-association rule; pathway; protein kinase;
Journal_Title :
Intelligent Systems, IEEE
DOI :
10.1109/MIS.2010.135
