Optical stimulation of primary motor cortex with 980nm infrared neural stimulation

To explore the penetration depth with short-wavelength infrared light, 980nm pulse infrared light was used to stimulate the primary motor cortex of rat. The heating model was created to simulate the temperature distribution for 1875nm and 980nm infrared neural stimulation. Post-stimulus time histogram was used to observe the neural response induced by Infrared neural stimulation on primary motor cortex. The model predicted the penetration depth of 980nm was deep into 1.2mm. Cortical neural located between 500μm to 1000μm were successfully activated by 980nm INS. The preliminary results suggested that, 980nm pulse INS could serve as a candidate for deep tissue stimulation.