• DocumentCode
    1416732
  • Title

    Addressing Neurological Disorders With Neuromodulation

  • Author

    Oluigbo, Chima O. ; Rezai, Ali R.

  • Author_Institution
    Dept. of Neurosurg., Ohio State Univ. Med. Center, Columbus, OH, USA
  • Volume
    58
  • Issue
    7
  • fYear
    2011
  • fDate
    7/1/2011 12:00:00 AM
  • Firstpage
    1907
  • Lastpage
    1917
  • Abstract
    Neurological disorders are becoming increasingly common in developed countries as a result of the aging population. In spite of medications, these disorders can result in progressive loss of function as well as chronic physical, cognitive, and emotional disability that ultimately places enormous emotional and economic on the patient, caretakers, and the society in general. Neuromodulation is emerging as a therapeutic option in these patients. Neuromodulation is a field, which involves implantable devices that allow for the reversible adjustable application of electrical, chemical, or biological agents to the central or peripheral nervous system with the objective of altering its functioning with the objective of achieving a therapeutic or clinically beneficial effect. It is a rapidly evolving field that brings together many different specialties in the fields of medicine, materials science, computer science and technology, biomedical, and neural engineering as well as the surgical or interventional specialties. It has multiple current and emerging indications, and an enormous potential for growth. The main challenges before it are in the need for effective collaboration between engineers, basic scientists, and clinicians to develop innovations that address specific problems resulting in new devices and clinical applications.
  • Keywords
    biochemistry; bioelectric phenomena; brain; cognition; electrochemistry; macromolecules; medical disorders; molecular biophysics; neuromuscular stimulation; prosthetics; aging population; biological agents; central nervous system; chemical agents; chronic physical disability; clinical applications; cognitive disability; electrical agents; electrical stimulation; emotional disability; implantable devices; neurological disorders; neuromodulation; patient therapy; peripheral nervous system; reversible adjustable application; Aging; Gerontology; Medical services; Neuromodulation; Neuromuscular; Neuromodulation; neurological disorders; Adult; Biomedical Engineering; Deep Brain Stimulation; Electric Stimulation Therapy; Electrodes, Implanted; Female; Humans; Infusion Pumps, Implantable; Male; Nerve Net; Nervous System Diseases; Neurosciences; Vagus Nerve Stimulation;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2010.2102758
  • Filename
    5678632