DocumentCode
1416732
Title
Addressing Neurological Disorders With Neuromodulation
Author
Oluigbo, Chima O. ; Rezai, Ali R.
Author_Institution
Dept. of Neurosurg., Ohio State Univ. Med. Center, Columbus, OH, USA
Volume
58
Issue
7
fYear
2011
fDate
7/1/2011 12:00:00 AM
Firstpage
1907
Lastpage
1917
Abstract
Neurological disorders are becoming increasingly common in developed countries as a result of the aging population. In spite of medications, these disorders can result in progressive loss of function as well as chronic physical, cognitive, and emotional disability that ultimately places enormous emotional and economic on the patient, caretakers, and the society in general. Neuromodulation is emerging as a therapeutic option in these patients. Neuromodulation is a field, which involves implantable devices that allow for the reversible adjustable application of electrical, chemical, or biological agents to the central or peripheral nervous system with the objective of altering its functioning with the objective of achieving a therapeutic or clinically beneficial effect. It is a rapidly evolving field that brings together many different specialties in the fields of medicine, materials science, computer science and technology, biomedical, and neural engineering as well as the surgical or interventional specialties. It has multiple current and emerging indications, and an enormous potential for growth. The main challenges before it are in the need for effective collaboration between engineers, basic scientists, and clinicians to develop innovations that address specific problems resulting in new devices and clinical applications.
Keywords
biochemistry; bioelectric phenomena; brain; cognition; electrochemistry; macromolecules; medical disorders; molecular biophysics; neuromuscular stimulation; prosthetics; aging population; biological agents; central nervous system; chemical agents; chronic physical disability; clinical applications; cognitive disability; electrical agents; electrical stimulation; emotional disability; implantable devices; neurological disorders; neuromodulation; patient therapy; peripheral nervous system; reversible adjustable application; Aging; Gerontology; Medical services; Neuromodulation; Neuromuscular; Neuromodulation; neurological disorders; Adult; Biomedical Engineering; Deep Brain Stimulation; Electric Stimulation Therapy; Electrodes, Implanted; Female; Humans; Infusion Pumps, Implantable; Male; Nerve Net; Nervous System Diseases; Neurosciences; Vagus Nerve Stimulation;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.2010.2102758
Filename
5678632
Link To Document