Title :
Integrated MOSFET-Embedded-Cantilever-Based Biosensor Characteristic for Detection of Anthrax Simulant
Author :
Mostafa, Salwa ; Lee, Ida ; Islam, Syed K. ; Eliza, Sazia A. ; Shekhawat, Gajendra ; Dravid, Vinayak P. ; Tulip, Fahmida S.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Univ. of Tennessee, Knoxville, TN, USA
fDate :
3/1/2011 12:00:00 AM
Abstract :
In this work, MOSFET-embedded cantilevers are configured as microbial sensors for detection of anthrax simulants, Bacillus thuringiensis. Anthrax simulants attached to the chemically treated gold-coated cantilever cause changes in the MOSFET drain current due to the bending of the cantilever which indicates the detection of anthrax simulant. Electrical properties of the anthrax simulant are also responsible for the change in the drain current. The test results suggest a detection range of 10 μL of stimulant test solution (a suspension population of 1.3 × 107 colony-forming units/mL diluted in 40% ethanol and 60% deionized water) with a linear response of 31 μA/μL.
Keywords :
MOSFET; biosensors; cantilevers; cellular biophysics; microorganisms; microsensors; molecular biophysics; suspensions; Bacillus thuringiensis; MOSFET drain current; anthrax simulants; deionized water; electrical properties; integrated MOSFET-embedded-cantilever-based biosensor; linear response; microbial sensors; suspension population; Anthrax simulant; MOSFET-embedded cantilever; biosensor;
Journal_Title :
Electron Device Letters, IEEE
DOI :
10.1109/LED.2010.2098015
