Title :
Synthesizing Distributions of Magnetic Nanoparticles for Clinical Hyperthermia
Author :
Barba, Paolo Di ; Dughiero, Fabrizio ; Sieni, Elisabetta
Author_Institution :
Dept. of Electr. Eng., Univ. of Pavia, Pavia, Italy
Abstract :
An automated procedure based on evolutionary computation and Finite Element Analysis (FEA) is proposed to synthesize the optimal distribution of nanoparticles (NPs) in multi-site injection for a Magnetic Fluid Hyperthermia (MFH) therapy. In particular a bi-objective formulation of the synthesis problem is considered taking into account both surface and volume temperature distribution in the tumor region.
Keywords :
finite element analysis; hyperthermia; magnetic fluids; magnetic particles; nanomagnetics; nanomedicine; nanoparticles; radiation therapy; tumours; FEA; clinical hyperthermia; finite element analysis; magnetic fluid hyperthermia therapy; magnetic nanoparticles; multisite injection; tumor region; volume temperature distribution; Heating; Hyperthermia; Magnetic resonance imaging; Nanoparticles; Optimization; Temperature distribution; Tumors; Finite-element field analysis; magnetic fluid hyperthermia; magnetic nanoparticles; optimization;
Journal_Title :
Magnetics, IEEE Transactions on
DOI :
10.1109/TMAG.2011.2174340
