Title :
Electric field stimulation of excitable tissue
Author :
Plonsey, Robert ; Burr, R.C.
Author_Institution :
Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA
Abstract :
The authors consider the determination of conditions when an excitable membrane can be considered linear and steady-state. The following topics are dealt with: threshold for a space-clamped fiber; threshold for a fiber stimulated by a point current source; subthreshold response; passive vs. active response; defibrillation stimulus-response time-constant; the transient intracellular current; the transient transmembrane potential due to junctional resistance.
Keywords :
bioelectric phenomena; biological effects of fields; biomembranes; cardiology; electric field effects; reviews; active response; cardiac electrophysiology; defibrillation stimulus-response time-constant; electric field stimulation; excitable tissue; junctional resistance; linear steady-state membrane; passive response; point current source; space-clamped fiber threshold; subthreshold response; transient intracellular current; transient transmembrane potential; Biomedical engineering; Biomembranes; Capacitance; Fault location; Geometry; Immune system; Kinetic theory; Threshold voltage; Animals; Biomedical Engineering; Electric Countershock; Electric Stimulation; Electrophysiology; Gap Junctions; Heart; Humans; Membrane Potentials; Models, Biological;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
