Title :
Quest for the Artificial Pancreas: Combining Technology with Treatment
Author :
Harvey, R.A. ; Youqing Wang ; Grosman, B. ; Percival, M.W. ; Bevier, W. ; Finan, D.A. ; Zisser, Howard ; Seborg, D.E. ; Jovanovic, L. ; Doyle, Francis J. ; Dassau, Eyal
Abstract :
The various components of the artificial pancreas puzzle are being put into place. Features such as communication, control, modeling, and learning are being realized presently. Steps have been set in motion to carry the conceptual design through simulation to clinical implementation. The challenging pieces still to be addressed include stress and exercise; as integral parts of the ultimate goal, effort has begun to shift toward overcoming the remaining hurdles to the full artificial pancreas. The artificial pancreas is close to becoming a reality, driven by technology, and the expectation that lives will be improved.
Keywords :
artificial organs; biochemistry; medical control systems; patient treatment; Type 1 diabetes mellitus; artificial pancreas; clinical implementation; conceptual design; continuous glucose monitor; continuous subcutaneous insulin infusion; exercise; patient treatment; stress; Biosensing Techniques; Biotechnology; Blood Glucose; Diabetes Mellitus, Type 1; Equipment Design; Humans; Pancreas, Artificial; Systems Integration;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2009.935711