Fourier Transform Light Scattering of Biological Structure and Dynamics

Author

Ding, Huafeng ; Berl, Ethan ; Wang, Zhuo ; Millet, Larry J. ; Gillette, Martha U. ; Liu, Jianming ; Boppart, Marni ; Popescu, Gabriel

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Illinois at Urbana-Champaign, Urbana, IL, USA

Volume

16

Issue

4

fYear

2010

Firstpage

909

Lastpage

918

Abstract

We review the principle and application of Fourier transform light scattering (FTLS), a new technique developed in our laboratory to study static and dynamic light scattering (DLS) from the biological tissues and live cells. The results demonstrate that FTLS has significant benefits over existing light scattering techniques in terms of sensitivity and resolution. We anticipate that FTLS will set the basis for disease diagnosis based on the intrinsic tissue optical properties and provide an efficient tool for quantifying cell structures and dynamics.

Keywords

Fourier transform optics; bio-optics; biological effects of optical radiation; biological tissues; cellular effects of radiation; diseases; light scattering; patient diagnosis; Fourier transform light scattering; biological cell; biological dynamics; biological structure; biological tissues; cell dynamics; cell structure; disease diagnosis; dynamic light scattering; static light scattering; tissue optical properties; Cells; Fourier transform light scattering (FTLS); light scattering; phase; quantitative phase imaging (QPI); tissue;

fLanguage

English

Journal_Title

Selected Topics in Quantum Electronics, IEEE Journal of

Publisher

ieee

ISSN

1077-260X

Type

jour

DOI

10.1109/JSTQE.2009.2034752

Filename

5443519