Title :
Closed- versus open-loop assessment of heart rate baroreflex
Author :
Barbieri, Riccardo ; Parati, Gianfranco ; Saul, J. Philip
Author_Institution :
Children´´s Heart Center, Med. Univ. of South Carolina, SC, USA
Abstract :
The autoregressive multivariate techniques described are based on simplified models of the entire cardiovascular system and satisfy both the requirements of not perturbing the system and providing a closed-loop evaluation of the interactions between R-R interval and arterial blood pressure. The closed-loop analysis is also able to calculate some of the indices previously used for baroreflex quantification, allowing for a direct comparison of the different approaches
Keywords :
autoregressive processes; biocontrol; blood vessels; cardiovascular system; feedback; feedforward; haemodynamics; identification; physiological models; spectral analysis; time series; transfer functions; R-R interval; abnormal blood pressure regulation; arterial blood pressure; autoregressive multivariate techniques; baroreflex quantification; black box model; cardiovascular system; closed-loop assessment; feedback; feedforward; heart rate baroreflex; identification; noise generated model; noninvasive assessment; normal blood pressure regulation; open-loop assessment; simplified models; time-variant analysis; transfer functions; Baroreflex; Blood pressure; Cardiology; Cardiovascular system; Frequency domain analysis; Gain measurement; Heart rate; Open loop systems; Signal processing; Transfer functions;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
