Extracting line representations of sulcal and gyral patterns in MR images of the human brain

This paper describes automatic procedures for extracting sulcal and gyral patterns from magnetic resonance (MR) images of the human brain. Specifically, the authors present three algorithms for the extraction of gyri, sulci, and sulcal fundi. These algorithms yield highly condensed line representations which can be used to describe the individual properties of the neocortical surface. The algorithms consist of a sequence of image analysis steps applied directly to the volumetric image data without requiring intermediate data representations such as surfaces or three-dimensional renderings. Previous studies have mostly focused on the extraction of surface representations, rather than line representations of cortical structures. The authors believe that line representations provide a valuable alternative to surface representations.